PGP9.5 Antibody

Catalog Number:

33472

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P09936
NCBI Gene ID: 7345

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human PGP9.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PGP9.5 protein.

Applications:

WB IHC

Background:

Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

Diana L. Mandelker, Cancer Res., Jun 2005; 65: 4963 - 4968.
Taiji Yamazaki, Clin. Cancer Res., Jan 2002; 8: 192.
Ekmel Tezel, Clin. Cancer Res., Dec 2000; 6: 4764.
Kenji Hibi, Am. J. Pathol., Sep 1999; 155: 711.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF