Product Datasheet  
PGP9.5 Antibody  
Catalog Number: 33472  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P09936
    NCBI Gene ID: 7345
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human PGP9.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • UCH-L1; neuron cytoplasmic protein 9.5; ubiquitin carboxyl-terminal hydrolase isozyme L1; ubiquitin thiolesterase L1;
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total PGP9.5 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.

    Diana L. Mandelker, Cancer Res., Jun 2005; 65: 4963 - 4968.
    Taiji Yamazaki, Clin. Cancer Res., Jan 2002; 8: 192.
    Ekmel Tezel, Clin. Cancer Res., Dec 2000; 6: 4764.
    Kenji Hibi, Am. J. Pathol., Sep 1999; 155: 711.




 
© Signalway Biotechnology All Rights Reserved.