GluR6 Antibody

Catalog Number:

33389

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O15303
NCBI Gene ID: 2916

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from human GluR6.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GluR6 protein.

Applications:

WB IHC

Background:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.

Inga Everts, J. Neurosci., Feb 1999; 19: 916.
Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 - 40173.
Sheng Yan, J. Neurosci., Jan 2004; 24: 679.
Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 - 17445.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF