Product Datasheet  
GluR6 Antibody  
Catalog Number: 33389  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O15303
    NCBI Gene ID: 2916
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from human GluR6.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
  • other_names：  
  • EAA4; GLR6; MGC74427; bA487F5.1 (glutamate receptor; ionotropic
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total GluR6 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity By similarity. Signaling stimulates TRPM1 channel activity and Ca2+ uptake. Required for normal vision.

    Inga Everts, J. Neurosci., Feb 1999; 19: 916.
    Gregory D. Salinas, J. Biol. Chem., Dec 2006; 281: 40164 - 40173.
    Sheng Yan, J. Neurosci., Jan 2004; 24: 679.
    Xiao-Mei Liu, J. Biol. Chem., Jun 2006; 281: 17432 - 17445.




 
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