Ezrin (Ab-478) Antibody

Catalog Number:

33213

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P15311
NCBI Gene ID: 7430

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 478 (P-V-Y(p)-E-P).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Ezrin protein.

Applications:

WB

Background:

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Gould K.L., EMBO J. 8:4133-4142(1989).
Turunen O., J. Biol. Chem. 264:16727-16732(1989).
Mungall A.J., Nature 425:805-811(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF