Product Datasheet  
Ezrin (Ab-478) Antibody  
Catalog Number: 33213  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P15311
    NCBI Gene ID: 7430
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 478 (P-V-Y(p)-E-P).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • Cytovillin; EZRI; p81; VIL2; Villin 2
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Ezrin protein.
  • Applications：  
  • WB
  • Background：  
  • Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

    Gould K.L., EMBO J. 8:4133-4142(1989).
    Turunen O., J. Biol. Chem. 264:16727-16732(1989).
    Mungall A.J., Nature 425:805-811(2003).



 
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