Synuclein-α (Ab-125) Antibody

Catalog Number:

33205

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P37840
NCBI Gene ID: 6622

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human Synuclein-α around the phosphorylation site of tyrosine 125 (E-A-Y(p)-E-M).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Synuclein-α protein.

Applications:

WB

Background:

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Ueda K., Proc. Natl. Acad. Sci. U.S.A. 90:11282-11286(1993).
Campion D., Genomics 26:254-257(1995).
Ueda K., Biochem. Biophys. Res. Commun. 205:1366-1372(1994).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF