Product Datasheet  
Synuclein-α (Ab-125) Antibody  
Catalog Number: 33205  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P37840
    NCBI Gene ID: 6622
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human Synuclein-α around the phosphorylation site of tyrosine 125 (E-A-Y(p)-E-M).
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000

  • other_names：  
  • alpha-synuclein; NACP; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; SYN
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total Synuclein-α protein.
  • Applications：  
  • WB
  • Background：  
  • May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

    Ueda K., Proc. Natl. Acad. Sci. U.S.A. 90:11282-11286(1993).
    Campion D., Genomics 26:254-257(1995).
    Ueda K., Biochem. Biophys. Res. Commun. 205:1366-1372(1994).



 
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