TRI18 Antibody

Catalog Number:

33578

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O15344
NCBI Gene ID: 4281

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TRI18.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRI18 protein.

Applications:

WB IHC IF

Background:

Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.

Quaderi N.A., Nat. Genet. 17:285-291(1997).
Perry J., Hum. Mol. Genet. 7:299-305(1998).
Van den Veyver I.B., Genomics 51:251-261(1998).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF