Product Datasheet  
TRI18 Antibody  
Catalog Number: 33578  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: O15344
    NCBI Gene ID: 4281
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized peptide derived from internal of human TRI18.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500~1:3000
    Immunohistochemistry: 1:50~1:100
    Immunofluorescence: 1:100~1:500
  • other_names：  
  • Midline-1; EC 6.3.2.-; Tripartite motif-containing protein 18; Putative transcription factor XPRF; Midin
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total TRI18 protein.
  • Applications：  
  • WB IHC IF
  • Background：  
  • Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.

    Quaderi N.A., Nat. Genet. 17:285-291(1997).
    Perry J., Hum. Mol. Genet. 7:299-305(1998).
    Van den Veyver I.B., Genomics 51:251-261(1998).




 
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