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Tubulin β Antibody

Catalog Number:

33532
other_names: TBB2; TBB5; TUBB; TUBB5; Tubulin beta chain

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13509
NCBI Gene ID: 10381

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human Tubulin β.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Tubulin β protein.

Applications:

WB IHC

Background:

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

J E Rudolph, Mol. Cell. Biol., Jun 1987; 7: 2231 - 2242.
Jong-Soo Chang, J. Biol. Chem., Feb 2005; 280: 6897 - 6905.
Virginie Redeker, J. Biol. Chem., Jan 2005; 280: 596 - 606.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

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