Product Datasheet
Tubulin β Antibody
Catalog Number: 33532
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: Q13509
NCBI Gene ID: 10381
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from C-terminal of human Tubulin β.
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- TBB2; TBB5; TUBB; TUBB5; Tubulin beta chain
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total Tubulin β protein.
- Background:
- Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
J E Rudolph, Mol. Cell. Biol., Jun 1987; 7: 2231 - 2242.
Jong-Soo Chang, J. Biol. Chem., Feb 2005; 280: 6897 - 6905.
Virginie Redeker, J. Biol. Chem., Jan 2005; 280: 596 - 606.
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