ATP1α1/Na+K+ ATPase1 (Ab-23) Antibody

Catalog Number:

33176

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P06685
NCBI Gene ID: 24211

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human ATP1α1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATP1α1/Na+K+ ATPase1 protein.

Applications:

WB IF

Background:

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

Shull G.E., Biochemistry 25:8125-8132(1986).
Hara Y., J. Biochem. 102:43-58(1987).
Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

Datasheet PDF