Product Datasheet  
ATP1α1/Na+K+ ATPase1 (Ab-23) Antibody  
Catalog Number: 33176  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P06685
    NCBI Gene ID: 24211
  • Form of Antibody：  
  • Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthesized non-phosphopeptide derived from human ATP1α1/Na+K+ ATPase1 around the phosphorylation site of serine 23 (K-K-S(p)-K-K).
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500~1:3000

    Immunofluorescence: 1:100~1:500
  • other_names：  
  • A1A1; AT1A1; ATPase; Na+/K+ transporting; alpha 1 polypeptide
  • Purification：  
  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Specificity：  
  • The antibody detects endogenous levels of total ATP1α1/Na+K+ ATPase1 protein.
  • Applications：  
  • WB IF
  • Background：  
  • This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

    Shull G.E., Biochemistry 25:8125-8132(1986).
    Hara Y., J. Biochem. 102:43-58(1987).
    Herrera V.L.M., J. Cell Biol. 105:1855-1865(1987).



 
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