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GATA3 Antibody

Catalog Number:

33160
other_names: GATA-binding factor 3; Trans-acting T-cell specific transcription factor GATA-3;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P23771/P23769
NCBI Gene ID: 2625

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human GATA3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GATA3 protein.

Applications:

WB IHC IF

Background:

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.

Dorota Kurek, Development, Jan 2007; 134: 261 - 272.
M. Andrew Nesbit, J. Biol. Chem., May 2004; 279: 22624 - 22634.
Wei Xu, Blood, May 2007; 109: 4406 - 4414.
David Grote, Development, Jan 2006; 133: 53 - 61.

References:

appl_detail:


Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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