Product Datasheet
GATA3 Antibody
Catalog Number: 33160
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P23771/P23769
NCBI Gene ID: 2625
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from Internal of human GATA3.
- appl_detail:
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
- other_names:
- GATA-binding factor 3; Trans-acting T-cell specific transcription factor GATA-3;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total GATA3 protein.
- Background:
- Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.
Dorota Kurek, Development, Jan 2007; 134: 261 - 272.
M. Andrew Nesbit, J. Biol. Chem., May 2004; 279: 22624 - 22634.
Wei Xu, Blood, May 2007; 109: 4406 - 4414.
David Grote, Development, Jan 2006; 133: 53 - 61.
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