STAT5B (Ab-731) Antibody

Catalog Number:

33126

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P51692
NCBI Gene ID: 6777

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized non-phosphopeptide derived from human STAT5B around the phosphorylation site of serine 731(A-P-S-P-A).

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STAT5B protein.

Applications:

WB IHC

Background:

Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.

Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002; 72: 819.
Stanislaw M. Stepkowski, Blood, Jan 2002; 99: 680 - 689.
Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003; 14: 40.

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF