Product Datasheet
STAT5B (Ab-731) Antibody
Catalog Number: 33126
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot: P51692
NCBI Gene ID: 6777
- Form of Antibody:
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Synthesized non-phosphopeptide derived from human STAT5B around the phosphorylation site of serine 731(A-P-S-P-A).
- appl_detail:
- Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
- other_names:
- Signal transducer and activator of transcription 5B;
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Specificity:
- The antibody detects endogenous levels of total STAT5B protein.
- Background:
- Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002; 72: 819.
Stanislaw M. Stepkowski, Blood, Jan 2002; 99: 680 - 689.
Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003; 14: 40.
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