IFNB1 Antibody

Catalog Number:

32320

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P01574
NCBI Gene ID:3456

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human IFNB1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total IFNB1 protein.

Applications:

WB

Background:

The genes encoding type I interferons (IFNs), which include 14 IFN-? genes, one IFN-¡Ò gene, one IFN-w (also known as IFN-? II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-? and -¡Ò are cytokines that are widely known to induce potent antiviral activity. IFN-? and -¡Ò exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-?, IFN-¡Ò or IFN-?, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-?R) interacts with IFN-?, IFN-¡Ò and IFN-w, and seems to be a multisubunit receptor.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF