Product Datasheet  
IFNB1 Antibody  
Catalog Number: 32320  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P01574
    NCBI Gene ID:3456
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein of human IFNB1.
  • reactivity：  
  • Human
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • IFNB1; IFB; IFF; IFNB; MGC96956
  • Purification：  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity：  
  • The antibody detects endogenous level of total IFNB1 protein.
  • Applications：  
  • WB
  • Background：  
  • The genes encoding type I interferons (IFNs), which include 14 IFN-? genes, one IFN-¡Ò gene, one IFN-w (also known as IFN-? II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-? and -¡Ò are cytokines that are widely known to induce potent antiviral activity. IFN-? and -¡Ò exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-?, IFN-¡Ò or IFN-?, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-?R) interacts with IFN-?, IFN-¡Ò and IFN-w, and seems to be a multisubunit receptor.



 
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