DEFB132 Antibody

Catalog Number:

32147

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q7Z7B7
NCBI Gene ID:400830

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human DEFB132.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total DEFB132 protein.

Applications:

WB IHC

Background:

¡Ò-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ¡Ò-defensins are developmentally regulated. The family of ¡Ò-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ¡Ò-defensins also are involved in sperm maturation and capacitation. ¡Ò-defensin 32, also known as ¡Ò-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.

References:

appl_detail:

Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100

Datasheet PDF