Product Datasheet  
DEFB132 Antibody  
Catalog Number: 32147  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q7Z7B7
    NCBI Gene ID:400830
  • Form of Antibody:  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein of human DEFB132.
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:500 - 1:2000
    Immunohistochemistry: 1:50 - 1:100
  • other_names:  
  • DEFB32; UNQ827;
  • Purification:  
  • Antibodies were purified by affinity purification using immunogen.
  • Specificity:  
  • The antibody detects endogenous level of total DEFB132 protein.
  • Applications:  
  • WB IHC
  • Background:  
  • ¡Ò-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ¡Ò-defensins are developmentally regulated. The family of ¡Ò-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ¡Ò-defensins also are involved in sperm maturation and capacitation. ¡Ò-defensin 32, also known as ¡Ò-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active.



 
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