IL6 Antibody

Catalog Number:

32064

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P05231
NCBI Gene ID:3569

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human IL6.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total IL6 protein.

Applications:

WB IHC

Background:

Interleukin-6 (IL6) is a multifunctional cytokine with a wide variety of biological functions. IL6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).

References:

appl_detail:

Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100

Datasheet PDF