Product Datasheet
IL6 Antibody
Catalog Number: 32064
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P05231
NCBI Gene ID:3569
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Recombinant protein of human IL6.
- appl_detail:
- Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100
- other_names:
- IL6; BSF2; HGF; HSF; IFNB2
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total IL6 protein.
- Background:
- Interleukin-6 (IL6) is a multifunctional cytokine with a wide variety of biological functions. IL6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).
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