PAFAH1B3 antibody

Catalog Number:

31990

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UJW9
NCBI Protein#: BC003016

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human PAFAH1B3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

WB, IHC

Background:

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.

References:

appl_detail:

WB dilution:1:1000-1:5000
IHC dilution:1:50-1:200

Datasheet PDF