Product Datasheet  
PAFAH1B3 antibody  
Catalog Number: 31990  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9UJW9
    NCBI Protein#: BC003016
  • Form of Antibody:  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Fusion protein of human PAFAH1B3
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB dilution:1:1000-1:5000
    IHC dilution:1:50-1:200
  • other_names:  
  • PAFAHG
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.



 
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