BTNL2 antibody

Catalog Number:

31977

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8NCC3
NCBI Protein#: BC127642

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human BTNL2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.?

References:

appl_detail:

IHC dilution:1:200-1:400

Datasheet PDF