Product Datasheet  
BTNL2 antibody  
Catalog Number: 31977  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8NCC3
    NCBI Protein#: BC127642
  • Form of Antibody：  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein of human BTNL2
  • reactivity：  
  • Hu
  • appl_detail：  

  • IHC dilution:1:200-1:400
  • other_names：  
  • SS2; BTN7; BTL-II; HSBLMHC1
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.?



 
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