ALDH1A1/ALDH1A2/ALDH1A3 antibody

Catalog Number:

31974

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q15102
NCBI Protein#: BC001505/BC030589/BC069274

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human ALDH1A1/ALDH1A2/ALDH1A3

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

WB, IHC

Background:

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

References:

appl_detail:

WB dilution:1:500-1:2000
IHC dilution:1:50-1:150

Datasheet PDF