Product Datasheet  
ALDH1A1/ALDH1A2/ALDH1A3 antibody  
Catalog Number: 31974  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q15102
    NCBI Protein#: BC001505/BC030589/BC069274
  • Form of Antibody:  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Fusion protein of human ALDH1A1/ALDH1A2/ALDH1A3
  • reactivity:  
  • Hu, Ms
  • appl_detail:  
  • WB dilution:1:500-1:2000
    IHC dilution:1:50-1:150
  • other_names:  
  • ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1; RALDH2, RALDH2-T, RALDH(II); ALDH6, RALDH3, ALDH1A6
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.



 
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