P3H2 antibody

Catalog Number:

31959

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q969R5
NCBI Gene ID: NP_060662

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Synthetic peptide of human P3H2

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

References:

appl_detail:

IHC dilution:1:50-1:100

Datasheet PDF