Product Datasheet  
P3H2 antibody  
Catalog Number: 31959  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q969R5
    NCBI Gene ID: NP_060662
  • Form of Antibody:  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Synthetic peptide of human P3H2
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  

  • IHC dilution:1:50-1:100
  • other_names:  
  • MCVD; MLAT4; LEPREL1
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.



 
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