DENND1A antibody

Catalog Number:

31843

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P09497
NCBI Protein#: BC039703

Form of Antibody:

pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Storage/Stability:

Immunogen:

Fusion protein of human DENND1A

Purification:

Antigen affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).

References:

appl_detail:

IHC dilution:1:50-1:200

Datasheet PDF