1-832-868-1888
order@swbio.com

Catalog Number: |
31813 |
| other_names: | GRAIL |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q9BRQ8 |
Form of Antibody: |
pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage/Stability: |
|
Immunogen: |
Fusion protein of human RNF128 |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
|
Applications: |
IHC |
Background: |
The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
References: |
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appl_detail: |
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