Product Datasheet  
RNF128 antibody  
Catalog Number: 31813  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9BRQ8
    NCBI Protein#: BC063404
  • Form of Antibody:  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Fusion protein of human RNF128
  • reactivity:  
  • Hu, Ms
  • appl_detail:  

  • IHC dilution:1:100-1:300
  • other_names:  
  • GRAIL
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • Applications:  
  • IHC
  • Background:  
  • The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.



 
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