1-832-868-1888
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Catalog Number: |
31812 |
| other_names: | GAP; S914; HA117 |
Amount: |
100μg |
| calculated_mw: | 54 kDa |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: O43865 |
Form of Antibody: |
pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage/Stability: |
|
Immunogen: |
Fusion protein of human RGS6 |
Purification: |
Antigen affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB, IHC |
Background: |
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known. |
References: |
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appl_detail: |
WB dilution:1:1000-1:5000 |
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