Product Datasheet  
RGS6 antibody  
Catalog Number: 31812  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O43865
    NCBI Protein#: BC113572
  • Form of Antibody：  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Fusion protein of human RGS6
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB dilution:1:1000-1:5000
    IHC dilution:1:50-1:300
  • other_names：  
  • GAP; S914; HA117
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • Applications：  
  • WB, IHC
  • Background：  
  • This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.



 
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