TXN Antibody

Catalog Number:

31296

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P10599
Gene ID:7295

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 90-105 amino acids of human thioredoxin

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total TXN protein.

Applications:

ELISA WB IHC

Background:

The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.

References:

appl_detail:

Predicted MW: 12kd
ELISA: 1:2000-1:10000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:50-1:200

Datasheet PDF