Product Datasheet  
TXN Antibody  
Catalog Number: 31296  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P10599
    Gene ID:7295
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 90-105 amino acids of human thioredoxin
  • reactivity：  
  • Hu
  • appl_detail：  
  • Predicted MW: 12kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:50-1:200
  • other_names：  
  • Thioredoxin, TRX; TRDX; TRX1
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total TXN protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.



 
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