AKR1C1 Antibody

Catalog Number:

31278

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q04828
Gene ID:1645

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 290-304 amino acids of human aldo-keto reductase family 1, member C1

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total AKR1C1 protein.

Applications:

ELISA WB IHC

Background:

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.?

References:

appl_detail:

Predicted MW: 37kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF