Product Datasheet  
AKR1C1 Antibody  
Catalog Number: 31278  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q04828
    Gene ID:1645
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 290-304 amino acids of human aldo-keto reductase family 1, member C1
  • reactivity：  
  • Hu Rt
  • appl_detail：  

  • Predicted MW: 37kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:50-1:200

  • other_names：  
  • Aldo-keto reductase family 1, member C1, C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total AKR1C1 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.?




 
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