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NFATC4 Antibody

Catalog Number:

31275
other_names: Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4, NFAT3; NF-ATc4

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q14934
Gene ID:4776

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 420-434 amino acids of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total NFATC4 protein.

Applications:

ELISA WB

Background:

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

References:

appl_detail:

Predicted MW: 102kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

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