Product Datasheet
NFATC4 Antibody
Catalog Number: 31275
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q14934
Gene ID:4776
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 420-434 amino acids of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
- appl_detail:
- Predicted MW: 102kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000
- other_names:
- Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4, NFAT3; NF-ATc4
- Specificity:
- The antibody detects endogenous level of total NFATC4 protein.
- Background:
- The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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