PDK4 Antibody

Catalog Number:

31258

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P52945
Gene ID:3651

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 101-113 amino acids of Human pyruvate dehydrogenase kinase, isozyme 4

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total PDK4 protein.

Applications:

ELISA WB IHC

Background:

This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

References:

appl_detail:

Predicted MW: 46kd
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF