Product Datasheet
PDK4 Antibody
Catalog Number: 31258
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P52945
Gene ID:3651
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Storage:
- Store at -20˚C/1 year
- Immunogen:
- Synthetic peptide corresponding to a region derived from 101-113 amino acids of Human pyruvate dehydrogenase kinase, isozyme 4
- other_names:
- Pyruvate dehydrogenase kinase, isozyme 4
- Specificity:
- The antibody detects endogenous level of total PDK4 protein.
- Applications:
- ELISA WB IHC
- Background:
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
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