CHRNA3 Antibody

Catalog Number:

31245

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P27348
Gene ID:10971

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 69-83 amino acids of Human cholinergic receptor, nicotinic, alpha 3 (neuronal)

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total CHRNA3 protein.

Applications:

ELISA WB IHC

Background:

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

References:

appl_detail:

Predicted MW: 55kd
ELISA: 1:2000-1:10000
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:15-1:50

Datasheet PDF