Product Datasheet  
CHRNA3 Antibody  
Catalog Number: 31245  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P27348
    Gene ID:10971
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C/1 year
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from 69-83 amino acids of Human cholinergic receptor, nicotinic, alpha 3 (neuronal)
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 55kd
    ELISA: 1:2000-1:10000
    Western blotting: 1:1000-1:5000
    Immunohistochemistry: 1:15-1:50

  • other_names：  
  • cholinergic receptor, nicotinic, alpha 3 (neuronal), LNCR2, PAOD2, NACHRA3
  • Purification：  
  • Specificity：  
  • The antibody detects endogenous level of total CHRNA3 protein.
  • Applications：  
  • ELISA WB IHC
  • Background：  

  • This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.




 
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