MMP17 Antibody

Catalog Number:

31237

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:P24347
Gene ID:4320

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide peptide corresponding to a region derived from 543-556 amino acids of human matrix metallopeptidase 17 (membrane-inserted)

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total MMP17 protein.

Applications:

ELISA WB

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.?

References:

appl_detail:

Predicted MW: 58kd
ELISA: 1:2000-1:5000
Western blotting: 1:500-1:2000

Datasheet PDF