Product Datasheet  
MMP17 Antibody  
Catalog Number: 31237  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P24347
    Gene ID:4320
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Synthetic peptide peptide corresponding to a region derived from 543-556 amino acids of human matrix metallopeptidase 17 (membrane-inserted)
  • reactivity:  
  • Hu
  • appl_detail:  
  • Predicted MW: 58kd
    ELISA: 1:2000-1:5000
    Western blotting: 1:500-1:2000
  • other_names:  
  • matrix metallopeptidase 17 (membrane-inserted), MT4-MMP
  • Purification:  
  • Specificity:  
  • The antibody detects endogenous level of total MMP17 protein.
  • Applications:  
  • ELISA WB
  • Background:  
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.?



 
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