HMGB2 Antibody

Catalog Number:

31219

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O14746
Gene ID:7015

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from 166-180 amino acids of Human high mobility group box 2

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of total HMGB2 protein.

Applications:

ELISA WB

Background:

This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

References:

appl_detail:

Predicted MW: 24kd
ELISA: 1:1000-1:10000
Western blotting: 1:2000-1:5000

Datasheet PDF